antidépresseurs tricycliques: à propos de trois cas d’intoxication volontaire Volume and tissue drug concentrations following fatal amitriptyline intoxication. Toxicité cardiovasculaire des antidépresseurs tricycliques: à propos de trois cas d’intoxication volontaire Volume 24, issue 3, Mai-Juin · PDF; Print; Save. Comment je traite l’intoxication aux antidépresseurs tricycliques: efficacité potentielle d’un traitement par émulsion lipidique.
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Physostigmine therapy in acute tricyclic antidepressant poisoning. Toxicity of tricyclic antidepressants. ECG changes in fatal imipramine Tofranil intoxication. Support Center Support Center. Central antidpdesseurs antagonism in Huntington’s chorea.
The main toxic manifestations are of anticholinergic origin, and the most frequent constitute the so-called central anticholinergic syndrome. Three cases are presented that illustrate chiefly the toxic manifestations related to the central nervous system. Reversal of tricyclic-overdosage-induced central anticholinergic syndrome by physostigmine. A dramatic response in a child resistant to other therapy. J Pharmacol Exp Ther.
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Intestinal absorption, demethylation, and enterohepatic circulation of imipramine. Myocardial damage due to imipramine intoxication. Cardiac abnormalities in poisoning with tricyclic antidepressants.
Tricyclic antidepressant overdoses in adolescent patients. Cardiovascular complications of antidepressant therapy. Copyright and License information Disclaimer. Open in a separate window.
Most of the deaths result from the cardiac complications. Interactions at the adrenergic neuron. Treatment of phenothiazine overdosage with physostigmine.
Usefulness of physostigmine in imipramine poisoning. National Center for Biotechnology InformationU. Reversal of coma, choreoathetosis, and myoclonus by physostigmine. Overdosage – the rise and fall of tricyclic antidepressants. Amitriptyline and imipramine poisoning in children. Am J Dis Child. Qualitative and quantitative studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
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Imipramine hydrochloride poisoning in childhood. Clinical effects and treatment of imipramine and amitriptyline poisoning in children. Reversal of central anticholinergic syndrome in man by physostigmine. Clin Pediatr Phila Dec; 15 Lipid hemodialysis versus charcoal hemoperfusion in imipramine poisoning.
The therapeutic management is reviewed in the light of the metabolism of the tricyclic antidepressants, their pharmacologic action and the mechanism of their toxic effects.
Abstract During the last decade there has been a substantial increase in intoxucation number of poisonings due to tricyclic antidepressants in both children and adults. Amitriptyline and imipramine poisoning. Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
The reversal of anticholinergic drug-induced delirium anidpresseurs coma with physostigmine. Physostigmine treatment of delirium induced by anticholinergics.